Galectin-1 confers resistance to doxorubicin in hepatocellular carcinoma cells through modulation of P-glycoprotein expression

Galectin-1 (GAL1), a β-galactoside-binding protein abundantly expressed in the tumor microenvironment, has emerged as a key mechanism of chemoresistance developed by different tumors. Although increased expression of GAL1 is a hallmark of hepatocellular carcinoma (HCC) progression, aggressiveness an...

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Detalles Bibliográficos
Autores principales: Carabias, Pablo, Espelt, María V., Bacigalupo, María L., Rojas, Paola, Sarrias, Luciana, Rubin, Ayelén, Saffioti, Nicolás A., Elola, María T., Rossi, Juan P., Wolfenstein-Todel, Carlota, Rabinovich, Gabriel A., Troncoso, María F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786848/
https://www.ncbi.nlm.nih.gov/pubmed/35075112
http://dx.doi.org/10.1038/s41419-022-04520-6

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