M-CSF supports medullary erythropoiesis and erythroid iron demand following burn injury through its activity on homeostatic iron recycling

M-CSF receptor signaling supports the development and survival of mononuclear phagocytes and is thought to play a role in post burn anemia by promoting myeloid lineage bias. We found M-CSF secretion was increased in burn patients and a murine model of post burn ACI, so we neutralized M-CSF in ACI mi...

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Detalles Bibliográficos
Autores principales: Noel, John G., Ramser, Seth W., Pitstick, Lori, Bonamer, John P., Mackenzie, Bryan, Seu, Katie G., Kalfa, Theodosia A., Cancelas, Jose A., Gardner, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786861/
https://www.ncbi.nlm.nih.gov/pubmed/35075211
http://dx.doi.org/10.1038/s41598-022-05360-2

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