Cargando…

Characterization of Monoclonal Antibody Glycan Heterogeneity Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry

Glycosylation is a critical quality attribute of monoclonal antibody (mAb) therapeutics. Hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) is an invaluable technology for the characterization of protein glycosylation. HILIC/MS-based glycan analysis relies on the library sear...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Sumit K., Lee, Kelvin H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786911/ https://www.ncbi.nlm.nih.gov/pubmed/35087805 http://dx.doi.org/10.3389/fbioe.2021.805788

Ejemplares similares

Mild Fractionation of Hydrophilic and Hydrophobic Components From Neochloris oleoabundans Using Ionic Liquids
por: Desai, Rupali K., et al.
Publicado: (2019)

Coupling Anion Exchange Chromatography with Native Mass Spectrometry for Charge Heterogeneity Characterization of Monoclonal Antibodies
por: Liu, Anita P., et al.
Publicado: (2022)

Maui-VIA: A User-Friendly Software for Visual Identification, Alignment, Correction, and Quantification of Gas Chromatography–Mass Spectrometry Data
por: Kuich, P. Henning J. L., et al.
Publicado: (2015)

In Planta Glycan Engineering and Functional Activities of IgE Antibodies
por: Montero-Morales, Laura, et al.
Publicado: (2019)

Standard Flow Liquid Chromatography for Shotgun Proteomics in Bioenergy Research
por: González Fernández-Niño, Susana M., et al.
Publicado: (2015)

Optimization of Glycolipid Synthesis in Hydrophilic Deep Eutectic Solvents
por: Hollenbach, Rebecca, et al.
Publicado: (2020)

Advanced Plant-Based Glycan Engineering
por: Montero-Morales, Laura, et al.
Publicado: (2018)

Strategies to Obtain Encapsulation and Controlled Release of Small Hydrophilic Molecules
por: Li, Qi, et al.
Publicado: (2020)

Determination of Oxidized Phosphatidylcholines by Hydrophilic Interaction Liquid Chromatography Coupled to Fourier Transform Mass Spectrometry
por: Sala, Pia, et al.
Publicado: (2015)

Analysis of sugars and amino acids in aphid honeydew by hydrophilic interaction liquid chromatography – Mass spectrometry
por: Nguyen, Phuong K., et al.
Publicado: (2020)

Circulating choline and phosphocholine measurement by a hydrophilic interaction liquid chromatography–tandem mass spectrometry
por: Guerra, Giulia, et al.
Publicado: (2023)

High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System
por: Diamos, Andrew G., et al.
Publicado: (2020)

Technological advances for analyzing the content of organ-on-a-chip by mass spectrometry
por: Hadavi, Darya, et al.
Publicado: (2023)

Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
por: Gao, Yuxiong, et al.
Publicado: (2021)

Use of Nanostructure-Initiator Mass Spectrometry to Deduce Selectivity of Reaction in Glycoside Hydrolases
por: Deng, Kai, et al.
Publicado: (2015)

Quantifying the Role of Lysine in Prion Replication by Nano-LC Mass Spectrometry and Bioassay
por: Silva, Christopher J., et al.
Publicado: (2020)

Lipid-Based Nanovesicles for Simultaneous Intracellular Delivery of Hydrophobic, Hydrophilic, and Amphiphilic Species
por: Zacheo, Antonella, et al.
Publicado: (2020)

Metabolic Footprint Analysis of Volatile Organic Compounds by Gas Chromatography-Ion Mobility Spectrometry to Discriminate Mandarin Fish (Siniperca chuatsi) at Different Fermentation Stages
por: Wang, Yueqi, et al.
Publicado: (2021)

A sensitive and rapid method of lead detection using nanoparticle technology based on monoclonal antibody
por: Jia, Kunzhi, et al.
Publicado: (2022)

Sensitive and rapid detection of tetrodotoxin based on gold nanoflower-and latex microsphere-labeled monoclonal antibodies
por: Huang, Yongming, et al.
Publicado: (2023)

DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry
por: Xiong, Jun, et al.
Publicado: (2015)

Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter
por: Buiarelli, Francesca, et al.
Publicado: (2018)

Rapid, direct, and sensitive determination of aziridine and 2-chloroethylamine by hydrophilic interaction liquid chromatography-mass spectrometry
por: Shackman, Jonathan G.
Publicado: (2019)

Analysis of amino acids in human tears by hydrophilic interaction liquid chromatography and quadrupole orbitrap mass spectrometry
por: Du, Chi-Xin, et al.
Publicado: (2019)

Determination of UDP-Glucose and UDP-Galactose in Maize by Hydrophilic Interaction Liquid Chromatography and Tandem Mass Spectrometry
por: Lan, Chen, et al.
Publicado: (2022)

Cell-mimicking polyethylene glycol-diacrylate based nanolipogel for encapsulation and delivery of hydrophilic biomolecule
por: Liew, Wen Jie Melvin, et al.
Publicado: (2023)

Isolation of a Monoclonal Antibody and its Derived Immunosensor for Rapid and Sensitive Detection of 17β-Estradiol
por: Liang, Jingru, et al.
Publicado: (2022)

Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products
por: Murisier, Amarande, et al.
Publicado: (2022)

Hyphenation of strong cation exchange chromatography to native mass spectrometry for high throughput online characterization of charge heterogeneity of therapeutic monoclonal antibodies
por: Ma, Fengfei, et al.
Publicado: (2020)

The Less the Better: How Suppressed Base Addition Boosts Production of Monoclonal Antibodies With Chinese Hamster Ovary Cells
por: Becker, Max, et al.
Publicado: (2019)

Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies
por: Liang, Kexue, et al.
Publicado: (2023)

Highly sensitive characterization of non-human glycan structures of monoclonal antibody drugs utilizing tandem mass spectrometry
por: She, Yi-Min, et al.
Publicado: (2022)

Characterizing Glioblastoma Heterogeneity via Single-Cell Receptor Quantification
por: Chen, Si, et al.
Publicado: (2018)

Enhanced Acylcarnitine Annotation in High-Resolution Mass Spectrometry Data: Fragmentation Analysis for the Classification and Annotation of Acylcarnitines
por: van der Hooft, Justin J. J., et al.
Publicado: (2015)

An evaluation of sucrose as a possible contaminant in e-liquids for electronic cigarettes by hydrophilic interaction liquid chromatography–tandem mass spectrometry
por: Kubica, Paweł, et al.
Publicado: (2014)

Predicting retention time in hydrophilic interaction liquid chromatography mass spectrometry and its use for peak annotation in metabolomics
por: Cao, Mingshu, et al.
Publicado: (2014)

Hydrophilic Interaction Liquid Chromatography Coupled to Mass Spectrometry and Multivariate Analysis of the De Novo Pyrimidine Pathway Metabolites
por: Galeano Garcia, Paula, et al.
Publicado: (2019)

Analysis of Non-Ionic Surfactant Triton X-100 Using Hydrophilic Interaction Liquid Chromatography and Mass Spectrometry
por: Farsang, Evelin, et al.
Publicado: (2019)

Comprehensive Identification of Glycosphingolipids in Human Plasma Using Hydrophilic Interaction Liquid Chromatography—Electrospray Ionization Mass Spectrometry
por: Hořejší, Karel, et al.
Publicado: (2021)

Direct injection analysis of oxypurinol and metformin in wastewater by hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry
por: Zheng, Qiuda, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2t5ega407aph0mu69ntgivcmql