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Loss of NEDD4 causes complete XY gonadal sex reversal in mice

Gonadogenesis is the process wherein two morphologically distinct organs, the testis and the ovary, arise from a common precursor. In mammals, maleness is driven by the expression of Sry. SRY subsequently upregulates the related family member Sox9 which is responsible for initiating testis different...

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Detalles Bibliográficos
Autores principales:	Windley, Simon P., Mayère, Chloé, McGovern, Alice E., Harvey, Natasha L., Nef, Serge, Schwarz, Quenten, Kumar, Sharad, Wilhelm, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786929/ https://www.ncbi.nlm.nih.gov/pubmed/35075134 http://dx.doi.org/10.1038/s41419-022-04519-z

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