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Structural basis of the ligand binding and signaling mechanism of melatonin receptors

Melatonin receptors (MT(1) and MT(2) in humans) are family A G protein–coupled receptors that respond to the neurohormone melatonin to regulate circadian rhythm and sleep. Numerous efforts have been made to develop drugs targeting melatonin receptors for the treatment of insomnia, circadian rhythm d...

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Detalles Bibliográficos
Autores principales:	Wang, Qinggong, Lu, Qiuyuan, Guo, Qiong, Teng, Maikun, Gong, Qingguo, Li, Xu, Du, Yang, Liu, Zheng, Tao, Yuyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786939/ https://www.ncbi.nlm.nih.gov/pubmed/35075127 http://dx.doi.org/10.1038/s41467-022-28111-3

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