Cargando…
Rapid estimation of viral emission source location via genetic algorithm
Indoor spread of infectious diseases is well-studied as a common transmission route. For highly infectious diseases, like Sars-CoV-2, considering poorly or semi ventilated areas outdoors is increasingly important. This is important in communities with high proportions of infected people, highly infe...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787039/ https://www.ncbi.nlm.nih.gov/pubmed/35095145 http://dx.doi.org/10.1007/s00466-021-02138-7 |
_version_ | 1784639272011169792 |
---|---|
author | Clemon, L. M. |
author_facet | Clemon, L. M. |
author_sort | Clemon, L. M. |
collection | PubMed |
description | Indoor spread of infectious diseases is well-studied as a common transmission route. For highly infectious diseases, like Sars-CoV-2, considering poorly or semi ventilated areas outdoors is increasingly important. This is important in communities with high proportions of infected people, highly infectious variants, or where spread is difficult to manage. This work develops a simulation framework based on probabilistic distributions of viral particles, decay, and infection. The methodology reduces the computational cost of generating rapid estimations of a wide variety of scenarios compared to other simulation methods with high computational cost and more fidelity. Outdoor predictions are provided in example applications for a gathering of five people with oscillating wind and a public speaking event. The results indicate that infection is sensitive to population density and outdoor transmission is plausible and likely locations of a virtual super-spreader are identified. Outdoor gatherings should consider precautions to reduce infection spread. |
format | Online Article Text |
id | pubmed-8787039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-87870392022-01-25 Rapid estimation of viral emission source location via genetic algorithm Clemon, L. M. Comput Mech Original Paper Indoor spread of infectious diseases is well-studied as a common transmission route. For highly infectious diseases, like Sars-CoV-2, considering poorly or semi ventilated areas outdoors is increasingly important. This is important in communities with high proportions of infected people, highly infectious variants, or where spread is difficult to manage. This work develops a simulation framework based on probabilistic distributions of viral particles, decay, and infection. The methodology reduces the computational cost of generating rapid estimations of a wide variety of scenarios compared to other simulation methods with high computational cost and more fidelity. Outdoor predictions are provided in example applications for a gathering of five people with oscillating wind and a public speaking event. The results indicate that infection is sensitive to population density and outdoor transmission is plausible and likely locations of a virtual super-spreader are identified. Outdoor gatherings should consider precautions to reduce infection spread. Springer Berlin Heidelberg 2022-01-25 2022 /pmc/articles/PMC8787039/ /pubmed/35095145 http://dx.doi.org/10.1007/s00466-021-02138-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Clemon, L. M. Rapid estimation of viral emission source location via genetic algorithm |
title | Rapid estimation of viral emission source location via genetic algorithm |
title_full | Rapid estimation of viral emission source location via genetic algorithm |
title_fullStr | Rapid estimation of viral emission source location via genetic algorithm |
title_full_unstemmed | Rapid estimation of viral emission source location via genetic algorithm |
title_short | Rapid estimation of viral emission source location via genetic algorithm |
title_sort | rapid estimation of viral emission source location via genetic algorithm |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787039/ https://www.ncbi.nlm.nih.gov/pubmed/35095145 http://dx.doi.org/10.1007/s00466-021-02138-7 |
work_keys_str_mv | AT clemonlm rapidestimationofviralemissionsourcelocationviageneticalgorithm |