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Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model

The loss of parvalbumin-positive (PV(+)) neurons in the substantia nigra pars reticulata (SNR) was observed in patients with end-stage Parkinson’s disease (PD) and our previously constructed old-aged Pitx3-A53Tα-Syn × Tau(–/–) triple transgenic mice model of PD. The aim of this study was to examine...

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Detalles Bibliográficos
Autores principales:	Zheng, Meige, Liu, Yanchang, Xiao, Zhaoming, Jiao, Luyan, Lin, Xian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787263/ https://www.ncbi.nlm.nih.gov/pubmed/35087392 http://dx.doi.org/10.3389/fnagi.2021.784665

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