A Single Cisterna Magna Injection of AAV Leads to Binaural Transduction in Mice

Viral-mediated gene augmentation, silencing, or editing offers tremendous promise for the treatment of inherited and acquired deafness. Inner-ear gene therapies often require a safe, clinically useable and effective route of administration to target both ears, while avoiding damage to the delicate s...

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Detalles Bibliográficos
Autores principales: Blanc, Fabian, Bemelmans, Alexis-Pierre, Affortit, Corentin, Joséphine, Charlène, Puel, Jean-Luc, Mondain, Michel, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787364/
https://www.ncbi.nlm.nih.gov/pubmed/35087833
http://dx.doi.org/10.3389/fcell.2021.783504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787364/
https://www.ncbi.nlm.nih.gov/pubmed/35087833
http://dx.doi.org/10.3389/fcell.2021.783504

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