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A Single Cisterna Magna Injection of AAV Leads to Binaural Transduction in Mice
Viral-mediated gene augmentation, silencing, or editing offers tremendous promise for the treatment of inherited and acquired deafness. Inner-ear gene therapies often require a safe, clinically useable and effective route of administration to target both ears, while avoiding damage to the delicate s...
Autores principales: | Blanc, Fabian, Bemelmans, Alexis-Pierre, Affortit, Corentin, Joséphine, Charlène, Puel, Jean-Luc, Mondain, Michel, Wang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787364/ https://www.ncbi.nlm.nih.gov/pubmed/35087833 http://dx.doi.org/10.3389/fcell.2021.783504 |
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