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N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition

The ongoing coronavirus (CoV) disease 2019 (COVID-19) pandemic caused by infection with severe acute respiratory syndrome CoV 2 (SARS-CoV-2) is associated with substantial morbidity and mortality. Understanding the immunological and pathological processes of coronavirus diseases is crucial for the r...

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Detalles Bibliográficos
Autores principales: Pan, Ruangang, Kindler, Eveline, Cao, Liu, Zhou, Yu, Zhang, Zhen, Liu, Qianyun, Ebert, Nadine, Züst, Roland, Sun, Ying, Gorbalenya, Alexander E., Perlman, Stanley, Thiel, Volker, Chen, Yu, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787479/
https://www.ncbi.nlm.nih.gov/pubmed/35073761
http://dx.doi.org/10.1128/mbio.03662-21

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