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Engineering T-Cell Resistance to HIV-1 Infection via Knock-In of Peptides from the Heptad Repeat 2 Domain of gp41

Previous studies suggest that short peptides from the heptad repeat 2 (HR2) domain of gp41 expressed on the cell surface are more potent inhibitors of HIV-1 entry than soluble analogs. However, their therapeutic potential has only been examined using lentiviral vectors. Here, we aimed to develop CRI...

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Detalles Bibliográficos
Autores principales:	Maslennikova, Alexandra, Kruglova, Natalia, Kalinichenko, Svetlana, Komkov, Dmitriy, Shepelev, Mikhail, Golubev, Dmitriy, Siniavin, Andrei, Vzorov, Andrei, Filatov, Alexander, Mazurov, Dmitriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787484/ https://www.ncbi.nlm.nih.gov/pubmed/35073736 http://dx.doi.org/10.1128/mbio.03589-21

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