Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A

COVID-19 has been associated with acral ischemia and digital necrosis. Standard treatment of acral ischemia and digital or acral necrosis includes ongoing therapy with vasodilators and anticoagulants. However, these treatments are not always efficient to avoid the progression of necroses, which in t...

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Autores principales: Schjødt, Mette Soelberg, Bech, Rikke, Braae Olesen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787540/
https://www.ncbi.nlm.nih.gov/pubmed/35111009
http://dx.doi.org/10.1159/000520589
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author Schjødt, Mette Soelberg
Bech, Rikke
Braae Olesen, Anne
author_facet Schjødt, Mette Soelberg
Bech, Rikke
Braae Olesen, Anne
author_sort Schjødt, Mette Soelberg
collection PubMed
description COVID-19 has been associated with acral ischemia and digital necrosis. Standard treatment of acral ischemia and digital or acral necrosis includes ongoing therapy with vasodilators and anticoagulants. However, these treatments are not always efficient to avoid the progression of necroses, which in the worst case can lead to amputation. Here, we report a case in which interdigital Botox<sup>®</sup> (botulinum toxin type A) nerve cord injection stopped the progression of acral necroses arising from an underlying vasculopathy due to COVID-19. Moreover, Botox<sup>®</sup> injection eliminated inflammation in the affected acral area within 2 weeks. This is the first case report to suggest Botox<sup>®</sup> injection as a new and improving treatment for acral necroses due to COVID-19.
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spelling pubmed-87875402022-02-01 Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A Schjødt, Mette Soelberg Bech, Rikke Braae Olesen, Anne Case Rep Dermatol Single Case COVID-19 has been associated with acral ischemia and digital necrosis. Standard treatment of acral ischemia and digital or acral necrosis includes ongoing therapy with vasodilators and anticoagulants. However, these treatments are not always efficient to avoid the progression of necroses, which in the worst case can lead to amputation. Here, we report a case in which interdigital Botox<sup>®</sup> (botulinum toxin type A) nerve cord injection stopped the progression of acral necroses arising from an underlying vasculopathy due to COVID-19. Moreover, Botox<sup>®</sup> injection eliminated inflammation in the affected acral area within 2 weeks. This is the first case report to suggest Botox<sup>®</sup> injection as a new and improving treatment for acral necroses due to COVID-19. S. Karger AG 2021-12-27 /pmc/articles/PMC8787540/ /pubmed/35111009 http://dx.doi.org/10.1159/000520589 Text en Copyright © 2021 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Schjødt, Mette Soelberg
Bech, Rikke
Braae Olesen, Anne
Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title_full Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title_fullStr Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title_full_unstemmed Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title_short Acral Necrosis in a COVID-19-Infected Man Treated with Botulinum Toxin Type A
title_sort acral necrosis in a covid-19-infected man treated with botulinum toxin type a
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787540/
https://www.ncbi.nlm.nih.gov/pubmed/35111009
http://dx.doi.org/10.1159/000520589
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AT braaeolesenanne acralnecrosisinacovid19infectedmantreatedwithbotulinumtoxintypea

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