Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials

It is suggested that dopaminergic treatment may contribute to accelerated improvement in patients with a disorder of consciousness (DoC). Dopamine is an important stimulatory neurotransmitter, which plays a key role in alertness, arousal, behavior, emotion, cognition, and motor function. We discuss...

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Autores principales: Saleh, Christian, Andrykiewicz, Agnieszka, Hund-Georgiadis, Margret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Case Series - General Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787551/
https://www.ncbi.nlm.nih.gov/pubmed/35111026
http://dx.doi.org/10.1159/000520435
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author Saleh, Christian
Andrykiewicz, Agnieszka
Hund-Georgiadis, Margret
author_facet Saleh, Christian
Andrykiewicz, Agnieszka
Hund-Georgiadis, Margret
author_sort Saleh, Christian
collection PubMed
description It is suggested that dopaminergic treatment may contribute to accelerated improvement in patients with a disorder of consciousness (DoC). Dopamine is an important stimulatory neurotransmitter, which plays a key role in alertness, arousal, behavior, emotion, cognition, and motor function. We discuss our experience with Madopar in 2 patients with DoC and review the literature on dopaminergic medication in patients with DoC.
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spelling pubmed-87875512022-02-01 Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials Saleh, Christian Andrykiewicz, Agnieszka Hund-Georgiadis, Margret Case Rep Neurol Case Series - General Neurology It is suggested that dopaminergic treatment may contribute to accelerated improvement in patients with a disorder of consciousness (DoC). Dopamine is an important stimulatory neurotransmitter, which plays a key role in alertness, arousal, behavior, emotion, cognition, and motor function. We discuss our experience with Madopar in 2 patients with DoC and review the literature on dopaminergic medication in patients with DoC. S. Karger AG 2021-12-16 /pmc/articles/PMC8787551/ /pubmed/35111026 http://dx.doi.org/10.1159/000520435 Text en Copyright © 2021 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Series - General Neurology
Saleh, Christian
Andrykiewicz, Agnieszka
Hund-Georgiadis, Margret
Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title_full Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title_fullStr Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title_full_unstemmed Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title_short Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials
title_sort does madopar have a role in the treatment of prolonged disorders of consciousness? a call for randomized controlled trials
topic Case Series - General Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787551/
https://www.ncbi.nlm.nih.gov/pubmed/35111026
http://dx.doi.org/10.1159/000520435
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