COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?

Through the ongoing and heightening coronavirus disease 2019 (COVID-19) pandemic, the heart has been implicated as a central target of injury associated with significantly increased morbidity and mortality. Correspondingly, heart transplant recipients are a vulnerable population for which insufficie...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanson, Paul J, Liu-Fei, Felicia, Lai, Chi, Toma, Mustafa, McManus, Bruce M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787635/
https://www.ncbi.nlm.nih.gov/pubmed/35083057
http://dx.doi.org/10.1093/omcr/omab143
_version_ 1784639400406155264
author Hanson, Paul J
Liu-Fei, Felicia
Lai, Chi
Toma, Mustafa
McManus, Bruce M
author_facet Hanson, Paul J
Liu-Fei, Felicia
Lai, Chi
Toma, Mustafa
McManus, Bruce M
author_sort Hanson, Paul J
collection PubMed
description Through the ongoing and heightening coronavirus disease 2019 (COVID-19) pandemic, the heart has been implicated as a central target of injury associated with significantly increased morbidity and mortality. Correspondingly, heart transplant recipients are a vulnerable population for which insufficient research has been conducted. Pathologic antibody-mediated rejection (pAMR) of cardiac allografts shares many characteristics with COVID-19-associated cardiac injury. In this case study, we investigate a 57-year-old female who contracted COVID-19 11 days postheart transplant and was observed to have pAMR while positive for laboratory-confirmed COVID-19, resulting in a diagnostic conundrum.
format Online
Article
Text
id pubmed-8787635
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-87876352022-01-25 COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury? Hanson, Paul J Liu-Fei, Felicia Lai, Chi Toma, Mustafa McManus, Bruce M Oxf Med Case Reports Case Report Through the ongoing and heightening coronavirus disease 2019 (COVID-19) pandemic, the heart has been implicated as a central target of injury associated with significantly increased morbidity and mortality. Correspondingly, heart transplant recipients are a vulnerable population for which insufficient research has been conducted. Pathologic antibody-mediated rejection (pAMR) of cardiac allografts shares many characteristics with COVID-19-associated cardiac injury. In this case study, we investigate a 57-year-old female who contracted COVID-19 11 days postheart transplant and was observed to have pAMR while positive for laboratory-confirmed COVID-19, resulting in a diagnostic conundrum. Oxford University Press 2022-01-24 /pmc/articles/PMC8787635/ /pubmed/35083057 http://dx.doi.org/10.1093/omcr/omab143 Text en © The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Hanson, Paul J
Liu-Fei, Felicia
Lai, Chi
Toma, Mustafa
McManus, Bruce M
COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title_full COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title_fullStr COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title_full_unstemmed COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title_short COVID-19-positivity in a heart transplant recipient—antibody-mediated rejection or SARS-CoV-2-associated cardiac injury?
title_sort covid-19-positivity in a heart transplant recipient—antibody-mediated rejection or sars-cov-2-associated cardiac injury?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787635/
https://www.ncbi.nlm.nih.gov/pubmed/35083057
http://dx.doi.org/10.1093/omcr/omab143
work_keys_str_mv AT hansonpaulj covid19positivityinahearttransplantrecipientantibodymediatedrejectionorsarscov2associatedcardiacinjury
AT liufeifelicia covid19positivityinahearttransplantrecipientantibodymediatedrejectionorsarscov2associatedcardiacinjury
AT laichi covid19positivityinahearttransplantrecipientantibodymediatedrejectionorsarscov2associatedcardiacinjury
AT tomamustafa covid19positivityinahearttransplantrecipientantibodymediatedrejectionorsarscov2associatedcardiacinjury
AT mcmanusbrucem covid19positivityinahearttransplantrecipientantibodymediatedrejectionorsarscov2associatedcardiacinjury

Ejemplares similares