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RNA-Binding Protein HuR Promotes Airway Inflammation in a House Dust Mite-Induced Allergic Asthma Model

Mounting evidence indicates that interleukin 17 (IL-17) is critically involved in the pathogenesis of severe asthma. We have previously reported that upon IL-17 stimulation, Act1, an IL-17-receptor-complex adaptor, directly binds to its target mRNAs and utilizes other proteins, such as HuR, to upreg...

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Detalles Bibliográficos
Autores principales: Herjan, Tomasz, Xiao, Jianxin, Dziendziel Kolanek, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787712/
https://www.ncbi.nlm.nih.gov/pubmed/35041516
http://dx.doi.org/10.1089/jir.2021.0171