4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase

[Image: see text] Bio-orthogonal chemistries have revolutionized many fields. For example, metabolic chemical reporters (MCRs) of glycosylation are analogues of monosaccharides that contain a bio-orthogonal functionality, such as azides or alkynes. MCRs are metabolically incorporated into glycoprote...

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Detalles Bibliográficos
Autores principales: Jackson, Emma G., Cutolo, Giuliano, Yang, Bo, Yarravarapu, Nageswari, Burns, Mary W. N., Bineva-Todd, Ganka, Roustan, Chloë, Thoden, James B., Lin-Jones, Halley M., van Kuppevelt, Toin H., Holden, Hazel M., Schumann, Benjamin, Kohler, Jennifer J., Woo, Christina M., Pratt, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787749/
https://www.ncbi.nlm.nih.gov/pubmed/34931806
http://dx.doi.org/10.1021/acschembio.1c00818

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