Lower versus higher oxygenation targets in critically ill patients with severe hypoxaemia: secondary Bayesian analysis to explore heterogeneous treatment effects in the Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU) trial

BACKGROUND: In the Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU) trial, a lower (8 kPa) vs a higher (12 kPa) PaO(2) target did not affect mortality amongst critically ill adult patients. We used Bayesian statistics to evaluate any heterogeneity in the effect of oxygenation target...

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Detalles Bibliográficos
Autores principales: Klitgaard, Thomas L., Schjørring, Olav L., Lange, Theis, Møller, Morten H., Perner, Anders, Rasmussen, Bodil S., Granholm, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Critical Care
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787771/
https://www.ncbi.nlm.nih.gov/pubmed/34674834
http://dx.doi.org/10.1016/j.bja.2021.09.010

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