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3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives

[Image: see text] In recent years, significant progress has been observed in the field of skin bioprinting, which has a huge potential to revolutionize the way of treatment in injury and surgery. Furthermore, it may be considered as an appropriate platform to perform the assessment and screening of...

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Autores principales: Olejnik, Anna, Semba, Julia Anna, Kulpa, Adam, Dańczak-Pazdrowska, Aleksandra, Rybka, Jakub Dalibor, Gornowicz-Porowska, Justyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787816/
https://www.ncbi.nlm.nih.gov/pubmed/34967598
http://dx.doi.org/10.1021/acssynbio.1c00547
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author Olejnik, Anna
Semba, Julia Anna
Kulpa, Adam
Dańczak-Pazdrowska, Aleksandra
Rybka, Jakub Dalibor
Gornowicz-Porowska, Justyna
author_facet Olejnik, Anna
Semba, Julia Anna
Kulpa, Adam
Dańczak-Pazdrowska, Aleksandra
Rybka, Jakub Dalibor
Gornowicz-Porowska, Justyna
author_sort Olejnik, Anna
collection PubMed
description [Image: see text] In recent years, significant progress has been observed in the field of skin bioprinting, which has a huge potential to revolutionize the way of treatment in injury and surgery. Furthermore, it may be considered as an appropriate platform to perform the assessment and screening of cosmetic and pharmaceutical formulations. Therefore, the objective of this paper was to review the latest advances in 3D bioprinting dedicated to skin applications. In order to explain the boundaries of this technology, the architecture and functions of the native skin were briefly described. The principles of bioprinting methods were outlined along with a detailed description of key elements that are required to fabricate the skin equivalents. Next, the overview of recent progress in 3D bioprinting studies was presented. The article also highlighted the potential applications of bioengineered skin substituents in various fields including regenerative medicine, modeling of diseases, and cosmetics/drugs testing. The advantages, limitations, and future directions of this technology were also discussed.
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spelling pubmed-87878162022-01-26 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives Olejnik, Anna Semba, Julia Anna Kulpa, Adam Dańczak-Pazdrowska, Aleksandra Rybka, Jakub Dalibor Gornowicz-Porowska, Justyna ACS Synth Biol [Image: see text] In recent years, significant progress has been observed in the field of skin bioprinting, which has a huge potential to revolutionize the way of treatment in injury and surgery. Furthermore, it may be considered as an appropriate platform to perform the assessment and screening of cosmetic and pharmaceutical formulations. Therefore, the objective of this paper was to review the latest advances in 3D bioprinting dedicated to skin applications. In order to explain the boundaries of this technology, the architecture and functions of the native skin were briefly described. The principles of bioprinting methods were outlined along with a detailed description of key elements that are required to fabricate the skin equivalents. Next, the overview of recent progress in 3D bioprinting studies was presented. The article also highlighted the potential applications of bioengineered skin substituents in various fields including regenerative medicine, modeling of diseases, and cosmetics/drugs testing. The advantages, limitations, and future directions of this technology were also discussed. American Chemical Society 2021-12-30 2022-01-21 /pmc/articles/PMC8787816/ /pubmed/34967598 http://dx.doi.org/10.1021/acssynbio.1c00547 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Olejnik, Anna
Semba, Julia Anna
Kulpa, Adam
Dańczak-Pazdrowska, Aleksandra
Rybka, Jakub Dalibor
Gornowicz-Porowska, Justyna
3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title_full 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title_fullStr 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title_full_unstemmed 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title_short 3D Bioprinting in Skin Related Research: Recent Achievements and Application Perspectives
title_sort 3d bioprinting in skin related research: recent achievements and application perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787816/
https://www.ncbi.nlm.nih.gov/pubmed/34967598
http://dx.doi.org/10.1021/acssynbio.1c00547
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