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Construction of a quadruple gene-deleted vaccine confers complete protective immunity against emerging PRV variant challenge in piglets

BACKGROUND: Pseudorabies virus (PRV) causes Aujeszky’s disease or pseudorabies (PR) in pigs worldwide, which leads to heavy economic losses to the swine industry. Pigs are the natural host, meanwhile, animals such as dogs, cats, foxes, rabbits, cattle and sheep are susceptible to infection. In 2011,...

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Detalles Bibliográficos
Autores principales: Sun, Leqiang, Tang, Yajie, Yan, Keji, Zhang, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8787898/
https://www.ncbi.nlm.nih.gov/pubmed/35078501
http://dx.doi.org/10.1186/s12985-022-01748-8