Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice

BACKGROUND: Red yeast rice (RYR), a nutraceutical with a profound cholesterol-lowering effect, was found to attenuate non-alcoholic fatty liver disease (NAFLD) in mice. Despite monacolin K in RYR being a specific inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMCGR), the mechanisms underly...

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Detalles Bibliográficos
Autores principales: Zou, Jian, Yan, Chunyan, Wan, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788078/
https://www.ncbi.nlm.nih.gov/pubmed/35078487
http://dx.doi.org/10.1186/s13020-022-00573-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788078/
https://www.ncbi.nlm.nih.gov/pubmed/35078487
http://dx.doi.org/10.1186/s13020-022-00573-z

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