Cargando…

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

African swine fever (ASF)—an aggressive infectious disease caused by the African swine fever virus (ASFV)—is significantly unfavorable for swine production. ASFV has a complex structure and encodes 150–167 proteins; however, the function of most of these proteins is unknown. This study identified AS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Keshan, Yang, Bo, Shen, Chaochao, Zhang, Ting, Hao, Yu, Zhang, Dajun, Liu, Huanan, Shi, Xijuan, Li, Guoli, Yang, Jinke, Li, Dan, Zhu, Zixiang, Tian, Hong, Yang, Fan, Ru, Yi, Cao, Wei Jun, Guo, Jianhong, He, Jijun, Zheng, Haixue, Liu, Xiangtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788333/ https://www.ncbi.nlm.nih.gov/pubmed/35076286 http://dx.doi.org/10.1128/mbio.02330-21

Ejemplares similares

African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1
por: Yang, Jinke, et al.
Publicado: (2023)

Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins
por: Yang, Bo, et al.
Publicado: (2021)

Deletions of MGF110-9L and MGF360-9L from African swine fever virus are highly attenuated in swine and confer protection against homologous challenge
por: Li, Dan, et al.
Publicado: (2023)

Proteins in pregnant swine serum promote the African swine fever virus replication: an iTRAQ-based quantitative proteomic analysis
por: Yang, Jinke, et al.
Publicado: (2023)

Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
por: Ding, Mingyang, et al.
Publicado: (2022)

Functional Analysis and Proteomics Profiling of Extracellular Vesicles From Swine Plasma Infected by African Swine Fever Virus
por: Xu, Guowei, et al.
Publicado: (2022)

Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine
por: Zhao, Dengshuai, et al.
Publicado: (2021)

Metabolomic analysis of pig spleen reveals African swine fever virus infection increased acylcarnitine levels to facilitate viral replication
por: Yang, Xing, et al.
Publicado: (2023)

Component Identification and Analysis of Vesicular Fluid From Swine Infected by Foot-and-Mouth Disease Virus
por: Zhang, Ting, et al.
Publicado: (2022)

Mechanism of interaction between virus and host is inferred from the changes of gene expression in macrophages infected with African swine fever virus CN/GS/2018 strain
por: Yang, Bo, et al.
Publicado: (2021)

Correction to: Mechanism of interaction between virus and host is inferred from the changes of gene expression in macrophages infected with African swine fever virus CN/GS/2018 strain
por: Yang, Bo, et al.
Publicado: (2021)

Sequential Deletions of Interferon Inhibitors MGF110-9L and MGF505-7R Result in Sterile Immunity against the Eurasia Strain of Africa Swine Fever
por: Ding, Mingyang, et al.
Publicado: (2022)

Identification and analysis of the interaction network of African swine fever virus D1133L with host proteins
por: Hao, Yu, et al.
Publicado: (2022)

In vitro and in vivo analyses of co-infections with peste des petits ruminants and capripox vaccine strains
por: Zhang, Dajun, et al.
Publicado: (2021)

Correction to: In vitro and in vivo analyses of co‑infections with peste des petits ruminants and capripox vaccine strains
por: Zhang, Dajun, et al.
Publicado: (2021)

African swine fever virus MGF-360-10L is a novel and crucial virulence factor that mediates ubiquitination and degradation of JAK1 by recruiting the E3 ubiquitin ligase HERC5
por: Li, Dan, et al.
Publicado: (2023)

Correction to: Intercellular transmission of Seneca Valley virus mediated by exosomes
por: Xu, Guowei, et al.
Publicado: (2020)

Intercellular transmission of Seneca Valley virus mediated by exosomes
por: Xu, Guowei, et al.
Publicado: (2020)

The Pseudoknot Region of the 5′ Untranslated Region Is a Determinant of Viral Tropism and Virulence of Foot-and-Mouth Disease Virus
por: Zhu, Zixiang, et al.
Publicado: (2019)

PI3K–Akt pathway-independent PIK3AP1 identified as a replication inhibitor of the African swine fever virus based on iTRAQ proteomic analysis
por: Yang, Bo, et al.
Publicado: (2023)

African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling
por: Li, Dan, et al.
Publicado: (2021)

Genetic Determinants of Altered Virulence of Type O Foot-and-Mouth Disease Virus
por: Yang, Fan, et al.
Publicado: (2020)

ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity
por: Hao, Yu, et al.
Publicado: (2022)

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β
por: Gao, Qi, et al.
Publicado: (2021)

Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of the TPL2 Trimer by Degradation of TPL2 To Evade Host Antiviral Immunity
por: Zhang, Keshan, et al.
Publicado: (2021)

Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes TPL2-Mediated Activation of the IRF3/IFN-β Signaling Pathway to Facilitate the Virus Replication
por: Hao, Junhong, et al.
Publicado: (2021)

Corrigendum: Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes TPL2-Mediated Activation of the IRF3/IFN-β Signaling Pathway to Facilitate the Virus Replication
por: Hao, Junhong, et al.
Publicado: (2021)

Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease Virus
por: Yang, Bo, et al.
Publicado: (2020)

DDX20: A Multifunctional Complex Protein
por: He, Lu, et al.
Publicado: (2023)

African Swine Fever Virus MGF360-14L Negatively Regulates Type I Interferon Signaling by Targeting IRF3
por: Wang, Yang, et al.
Publicado: (2022)

Foot-and-Mouth Disease Virus Viroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of Its Protein Expression
por: Zhu, Zixiang, et al.
Publicado: (2016)

FoxJ1 inhibits African swine fever virus replication and viral S273R protein decreases the expression of FoxJ1 to impair its antiviral effect
por: Ma, Caina, et al.
Publicado: (2022)

African swine fever virus MGF360-11L negatively regulates cGAS-STING-mediated inhibition of type I interferon production
por: Yang, Kaidian, et al.
Publicado: (2022)

Review of Seneca Valley Virus: A Call for Increased Surveillance and Research
por: Zhang, Xiangle, et al.
Publicado: (2018)

Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report
por: Zhang, Keshan, et al.
Publicado: (2010)

African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway
por: Zhuo, Yisha, et al.
Publicado: (2020)

Identification of African swine fever virus MGF505-2R as a potent inhibitor of innate immunity in vitro
por: Huang, Huaguo, et al.
Publicado: (2022)

African Swine Fever Virus F317L Protein Inhibits NF-κB Activation To Evade Host Immune Response and Promote Viral Replication
por: Yang, Jinping, et al.
Publicado: (2021)

Erratum: Ramirez-Medina, E.; et al. Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene. Viruses 2020, 12, 1193
por: Editorial Office, Viruses
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0fq0a3hq91c4tqg5h7csp5hvqb