Cargando…

Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review

Background: In cases with solid tumors, preoperative radiological investigations provide valuable information on the anatomy of the tumor and the adjoining structures, thus helping in operative planning. However, due to a two-dimensional view in these investigations, a detailed spatial relationship...

Descripción completa

Detalles Bibliográficos
Autores principales: Anand, Sachit, Krishnan, Nellai, Goel, Prabudh, Dhua, Anjan Kumar, Jain, Vishesh, Yadav, Devendra Kumar, Bajpai, Minu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788437/
https://www.ncbi.nlm.nih.gov/pubmed/35076594
http://dx.doi.org/10.3390/pediatric14010006
_version_ 1784639564282855424
author Anand, Sachit
Krishnan, Nellai
Goel, Prabudh
Dhua, Anjan Kumar
Jain, Vishesh
Yadav, Devendra Kumar
Bajpai, Minu
author_facet Anand, Sachit
Krishnan, Nellai
Goel, Prabudh
Dhua, Anjan Kumar
Jain, Vishesh
Yadav, Devendra Kumar
Bajpai, Minu
author_sort Anand, Sachit
collection PubMed
description Background: In cases with solid tumors, preoperative radiological investigations provide valuable information on the anatomy of the tumor and the adjoining structures, thus helping in operative planning. However, due to a two-dimensional view in these investigations, a detailed spatial relationship is difficult to decipher. In contrast, three-dimensional (3D) printing technology provides a precise topographic view to perform safe surgical resections of these tumors. This systematic review aimed to summarize and analyze current evidence on the utility of 3D printing in pediatric extra-cranial solid tumors. Methods: The present study was registered on PROSPERO—international prospective register of systematic reviews (registration number: CRD42020206022). PubMed, Embase, SCOPUS, and Google Scholar databases were explored with appropriate search criteria to select the relevant studies. Data were extracted to study the bibliographic information of each article, the number of patients in each study, age of the patient(s), type of tumor, organ of involvement, application of 3D printing (surgical planning, training, and/or parental education). The details of 3D printing, such as type of imaging used, software details, printing technique, printing material, and cost were also synthesized. Results: Eight studies were finally included in the systematic review. Three-dimensional printing technology was used in thirty children with Wilms tumor (n = 13), neuroblastoma (n = 7), hepatic tumors (n = 8), retroperitoneal tumor (n = 1), and synovial sarcoma (n = 1). Among the included studies, the technology was utilized for preoperative surgical planning (five studies), improved understanding of the surgical anatomy of solid organs (two studies), and improving the parental understanding of the tumor and its management (one study). Computed tomography and magnetic resonance imaging were either performed alone or in combination for radiological evaluation in these children. Different types of printers and printing materials were used in the included studies. The cost of the 3D printed models and time involved (range 10 h to 4–5 days) were reported by two studies each. Conclusions: 3D printed models can be of great assistance to pediatric surgeons in understanding the spatial relationships of tumors with the adjacent anatomic structures. They also facilitate the understanding of families, improving doctor–patient communication.
format Online
Article
Text
id pubmed-8788437
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87884372022-01-26 Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review Anand, Sachit Krishnan, Nellai Goel, Prabudh Dhua, Anjan Kumar Jain, Vishesh Yadav, Devendra Kumar Bajpai, Minu Pediatr Rep Systematic Review Background: In cases with solid tumors, preoperative radiological investigations provide valuable information on the anatomy of the tumor and the adjoining structures, thus helping in operative planning. However, due to a two-dimensional view in these investigations, a detailed spatial relationship is difficult to decipher. In contrast, three-dimensional (3D) printing technology provides a precise topographic view to perform safe surgical resections of these tumors. This systematic review aimed to summarize and analyze current evidence on the utility of 3D printing in pediatric extra-cranial solid tumors. Methods: The present study was registered on PROSPERO—international prospective register of systematic reviews (registration number: CRD42020206022). PubMed, Embase, SCOPUS, and Google Scholar databases were explored with appropriate search criteria to select the relevant studies. Data were extracted to study the bibliographic information of each article, the number of patients in each study, age of the patient(s), type of tumor, organ of involvement, application of 3D printing (surgical planning, training, and/or parental education). The details of 3D printing, such as type of imaging used, software details, printing technique, printing material, and cost were also synthesized. Results: Eight studies were finally included in the systematic review. Three-dimensional printing technology was used in thirty children with Wilms tumor (n = 13), neuroblastoma (n = 7), hepatic tumors (n = 8), retroperitoneal tumor (n = 1), and synovial sarcoma (n = 1). Among the included studies, the technology was utilized for preoperative surgical planning (five studies), improved understanding of the surgical anatomy of solid organs (two studies), and improving the parental understanding of the tumor and its management (one study). Computed tomography and magnetic resonance imaging were either performed alone or in combination for radiological evaluation in these children. Different types of printers and printing materials were used in the included studies. The cost of the 3D printed models and time involved (range 10 h to 4–5 days) were reported by two studies each. Conclusions: 3D printed models can be of great assistance to pediatric surgeons in understanding the spatial relationships of tumors with the adjacent anatomic structures. They also facilitate the understanding of families, improving doctor–patient communication. MDPI 2022-01-11 /pmc/articles/PMC8788437/ /pubmed/35076594 http://dx.doi.org/10.3390/pediatric14010006 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Anand, Sachit
Krishnan, Nellai
Goel, Prabudh
Dhua, Anjan Kumar
Jain, Vishesh
Yadav, Devendra Kumar
Bajpai, Minu
Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title_full Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title_fullStr Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title_full_unstemmed Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title_short Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review
title_sort utility of three-dimensional printing for preoperative assessment of children with extra-cranial solid tumors: a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788437/
https://www.ncbi.nlm.nih.gov/pubmed/35076594
http://dx.doi.org/10.3390/pediatric14010006
work_keys_str_mv AT anandsachit utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT krishnannellai utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT goelprabudh utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT dhuaanjankumar utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT jainvishesh utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT yadavdevendrakumar utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview
AT bajpaiminu utilityofthreedimensionalprintingforpreoperativeassessmentofchildrenwithextracranialsolidtumorsasystematicreview