Structural Analysis of SMYD3 Lysine Methyltransferase for the Development of Competitive and Specific Enzyme Inhibitors

Lysine methylation is among the key posttranslational modifications to histones that contribute to epigenetic regulation. SMYD3 is a lysine methyltransferase that is essential for the proliferation of a range of tumorigenic cells. The findings that SMYD3 is significantly upregulated in most colorect...

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Detalles Bibliográficos
Autores principales: Jarrell, Dillon K., Hassell, Kelly N., Alshiraihi, Ilham, Crans, Debbie C., Brown, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788566/
https://www.ncbi.nlm.nih.gov/pubmed/35076487
http://dx.doi.org/10.3390/diseases10010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788566/
https://www.ncbi.nlm.nih.gov/pubmed/35076487
http://dx.doi.org/10.3390/diseases10010004

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