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Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance

Basal expression of the P2X7 receptor (P2X7R) improves mitochondrial metabolism, Adenosine 5′-triphosphate (ATP) synthesis, and overall fitness of immune and non-immune cells. We investigated P2X7R contribution to energy metabolism and subcellular localization in fibroblasts (mouse embryo fibroblast...

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Detalles Bibliográficos
Autores principales: Sarti, Alba Clara, Vultaggio-Poma, Valentina, Falzoni, Simonetta, Missiroli, Sonia, Giuliani, Anna Lisa, Boldrini, Paola, Bonora, Massimo, Faita, Francesco, Di Lascio, Nicole, Kusmic, Claudia, Solini, Anna, Novello, Salvatore, Morari, Michele, Rossato, Marco, Wieckowski, Mariusz R, Giorgi, Carlotta, Pinton, Paolo, Di Virgilio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788778/
https://www.ncbi.nlm.nih.gov/pubmed/35330818
http://dx.doi.org/10.1093/function/zqab005