Kv1.3 Channel Inhibition Limits Uremia-Induced Calcification in Mouse and Human Vascular Smooth Muscle

Chronic kidney disease (CKD) significantly increases cardiovascular risk. In advanced CKD stages, accumulation of toxic circulating metabolites and mineral metabolism alterations triggers vascular calcification, characterized by vascular smooth muscle cell (VSMC) transdifferentiation and loss of the...

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Detalles Bibliográficos
Autores principales: Cazaña-Pérez, Violeta, Cidad, Pilar, Navarro-González, Juan F, Rojo-Mencía, Jorge, Jaisser, Frederic, López-López, José R, Alvarez de la Rosa, Diego, Giraldez, Teresa, Pérez-García, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788811/
https://www.ncbi.nlm.nih.gov/pubmed/35330975
http://dx.doi.org/10.1093/function/zqaa036

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