Cargando…

Epigenetics and Beyond: Targeting Histone Methylation to Treat Type 2 Diabetes Mellitus

Diabetes mellitus is a global public health challenge with high morbidity. Type 2 diabetes mellitus (T2DM) accounts for 90% of the global prevalence of diabetes. T2DM is featured by a combination of defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yang, Luan, Ying, Feng, Qi, Chen, Xing, Qin, Bo, Ren, Kai-Di, Luan, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788853/ https://www.ncbi.nlm.nih.gov/pubmed/35087408 http://dx.doi.org/10.3389/fphar.2021.807413

Ejemplares similares

New Insight in HDACs: Potential Therapeutic Targets for the Treatment of Atherosclerosis
por: Luan, Yi, et al.
Publicado: (2022)

Histone Methylation Related Therapeutic Challenge in Cardiovascular Diseases
por: Yang, Yang, et al.
Publicado: (2021)

Exploring cuproptosis as a mechanism and potential intervention target in cardiovascular diseases
por: Yang, Yang, et al.
Publicado: (2023)

Rhein for treating diabetes mellitus: A pharmacological and mechanistic overview
por: Deng, Tingting, et al.
Publicado: (2023)

Histone modification and histone modification-targeted anti-cancer drugs in breast cancer: Fundamentals and beyond
por: Feng, Jianwei, et al.
Publicado: (2022)

Emerging Applications of Metabolomics to Assess the Efficacy of Traditional Chinese Medicines for Treating Type 2 Diabetes Mellitus
por: Zhang, Yumeng, et al.
Publicado: (2021)

Study on the mechanism of American ginseng extract for treating type 2 diabetes mellitus based on metabolomics
por: Liu, Tiantian, et al.
Publicado: (2022)

Emerging Role of Mitophagy in the Heart: Therapeutic Potentials to Modulate Mitophagy in Cardiac Diseases
por: Luan, Yi, et al.
Publicado: (2021)

Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review
por: Ran, Qian, et al.
Publicado: (2019)

The Potential Roles of Artemisinin and Its Derivatives in the Treatment of Type 2 Diabetes Mellitus
por: Jiang, Ya-yi, et al.
Publicado: (2020)

Discovery of Novel Biomarkers of Therapeutic Responses in Han Chinese Pemetrexed-Based Treated Advanced NSCLC Patients
por: Zhang, Xiaoqing, et al.
Publicado: (2019)

Mitochondrial Dynamics: Pathogenesis and Therapeutic Targets of Vascular Diseases
por: Luan, Yi, et al.
Publicado: (2021)

Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF–HuR complex
por: Zhu, Qi, et al.
Publicado: (2022)

The Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases
por: Monayo, Seth Mikaye, et al.
Publicado: (2022)

Epigenetic Alterations in Podocytes in Diabetic Nephropathy
por: Sugita, Erina, et al.
Publicado: (2021)

Epigenetic Studies of Chinese Herbal Medicine: Pleiotropic Role of DNA Methylation
por: Guo, Wenqian, et al.
Publicado: (2021)

Corrigendum: Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF–HuR complex
por: Zhu, Qi, et al.
Publicado: (2022)

Statins and New-Onset Diabetes Mellitus: LDL Receptor May Provide a Key Link
por: Yu, Qi, et al.
Publicado: (2017)

The protective effect of natural medicines against excessive inflammation and oxidative stress in acute lung injury by regulating the Nrf2 signaling pathway
por: Luan, Rumei, et al.
Publicado: (2022)

Endothelial heterogeneity in the umbilico-placental unit: DNA methylation as an innuendo of epigenetic diversity
por: Casanello, Paola, et al.
Publicado: (2014)

Herbal tea, a novel adjuvant therapy for treating type 2 diabetes mellitus: A review
por: Zhang, Xiangyuan, et al.
Publicado: (2022)

The Histone Deacetylase Inhibitor I1 Induces Differentiation of Acute Leukemia Cells With MLL Gene Rearrangements via Epigenetic Modification
por: Yao, Jingfang, et al.
Publicado: (2022)

Epigenetics in psychiatry: Beyond DNA methylation
por: Kouter, Katarina, et al.
Publicado: (2023)

Bladder Dysfunction in Diabetes Mellitus
por: Golbidi, Saeid, et al.
Publicado: (2010)

Association Between Folic Acid Supplementation and Retinal Atherosclerosis in Chinese Adults With Hypertension Complicated by Diabetes Mellitus
por: Meng, Ying, et al.
Publicado: (2018)

Epigenetic signatures of gestational diabetes mellitus on cord blood methylation
por: Haertle, Larissa, et al.
Publicado: (2017)

Editorial: Natural compounds regulating epigenetics for treating chronic inflammatory diseases
por: Zhang, Mingyu, et al.
Publicado: (2023)

Gut microbiota: A new therapeutic target for diabetic cardiomyopathy
por: Yuan, Suxin, et al.
Publicado: (2022)

Pyroptosis-Related Inflammasome Pathway: A New Therapeutic Target for Diabetic Cardiomyopathy
por: Cai, Zhengyao, et al.
Publicado: (2022)

Efficacy and mechanism of Jiedu Tongluo Tiaogan Formula in treating type 2 diabetes mellitus combined with non-alcoholic fatty liver disease: Study protocol for a parallel-armed, randomized controlled trial
por: Xu, Jinghan, et al.
Publicado: (2022)

Multi-Omics Comparison of the Spontaneous Diabetes Mellitus and Diet-Induced Prediabetic Macaque Models
por: Yang, Zhu, et al.
Publicado: (2021)

Traditional Chinese Medicine: A Class of Potentially Reliable Epigenetic Drugs
por: Zhu, Daoqi, et al.
Publicado: (2022)

Estrogen Receptor-Related DNA and Histone Methylation May Be Involved in the Transgenerational Disruption in Spermatogenesis by Selective Toxic Chemicals
por: Han, Xiao, et al.
Publicado: (2019)

The Potential of Anti-Diabetic Rākau Rongoā (Māori Herbal Medicine) to Treat Type 2 Diabetes Mellitus (T2DM) Mate Huka: A Review
por: Koia, Jonni Hazeline, et al.
Publicado: (2020)

The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine
por: Ma, Xueling, et al.
Publicado: (2018)

N6-methyladenine RNA Methylation Epigenetic Modification and Kidney Diseases
por: Luan, Junjun, et al.
Publicado: (2022)

Targets in Epigenetics: Inhibiting the Methyl Writers of the Histone Code
por: Yost, Julianne M, et al.
Publicado: (2011)

Tackling malignant melanoma epigenetically: histone lysine methylation
por: Orouji, Elias, et al.
Publicado: (2018)

Polysaccharides from natural resource: ameliorate type 2 diabetes mellitus via regulation of oxidative stress network
por: He, Li-Ying, et al.
Publicado: (2023)

17α-Hydroxyprogesterone Caproate Inhibits Cytokine Production via Suppression of NF-κB Activation
por: Hu, Tao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3fc2vrp3r3u2eljte90mqlrvb2