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IUGR with catch-up growth programs impaired insulin sensitivity through LRP6/IRS-1 in male rats

Intrauterine growth restriction combined with postnatal accelerated growth (CG-IUGR) could lead to long-term detrimental metabolic outcomes characterized by insulin resistance. As an indispensable co-receptor of Wnt signaling, LRP6 plays a critical role in the susceptibility of metabolic disorders....

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Detalles Bibliográficos
Autores principales: Long, Wenjun, Zhou, Tuo, Xuan, Xiuping, Cao, Qiuli, Luo, Zuojie, Qin, Yingfen, Ning, Qin, Luo, Xiaoping, Xie, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789020/
https://www.ncbi.nlm.nih.gov/pubmed/34825892
http://dx.doi.org/10.1530/EC-21-0203