Cargando…
Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA
Intronic splicing enhancers and silencers (ISEs and ISSs) are two groups of splicing-regulatory elements (SREs) that play critical roles in determining splice-site selection, particularly for alternatively spliced introns or exons. SREs are often short motifs; their mutation or dysregulation of thei...
Autores principales: | Gao, Yuan, Lin, Kuan-Ting, Jiang, Tao, Yang, Yang, Rahman, Mohammad A, Gong, Shuaishuai, Bai, Jialin, Wang, Li, Sun, Junjie, Sheng, Lei, Krainer, Adrian R, Hua, Yimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789036/ https://www.ncbi.nlm.nih.gov/pubmed/35018432 http://dx.doi.org/10.1093/nar/gkab1280 |
Ejemplares similares
-
Reactive astrocytes in ALS display diminished intron retention
por: Ziff, Oliver J, et al.
Publicado: (2021) -
Comprehensive characterization of somatic variants associated with intronic polyadenylation in human cancers
por: Zhao, Zhaozhao, et al.
Publicado: (2021) -
Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements
por: Ehmsen, Kirk T, et al.
Publicado: (2021) -
Macrophage development and activation involve coordinated intron retention in key inflammatory regulators
por: Green, Immanuel D, et al.
Publicado: (2020) -
Primary transcriptome and translatome analysis determines transcriptional and translational regulatory elements encoded in the Streptomyces clavuligerus genome
por: Hwang, Soonkyu, et al.
Publicado: (2019)