Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon

Eukaryotic genomes harbor hundreds of rRNA genes, many of which are transcriptionally silent. However, little is known about selective regulation of individual rDNA units. In Drosophila melanogaster, some rDNA repeats contain insertions of the R2 retrotransposon, which is capable to be transcribed o...

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Detalles Bibliográficos
Autores principales: Fefelova, Elena A, Pleshakova, Irina M, Mikhaleva, Elena A, Pirogov, Sergei A, Poltorachenko, Valentin A, Abramov, Yuri A, Romashin, Daniil D, Shatskikh, Aleksei S, Blokh, Roman S, Gvozdev, Vladimir A, Klenov, Mikhail S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789037/
https://www.ncbi.nlm.nih.gov/pubmed/35037046
http://dx.doi.org/10.1093/nar/gkab1276

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