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Directed evolution of orthogonal RNA–RBP pairs through library-vs-library in vitro selection
RNA-binding proteins (RBPs) and their RNA ligands play many critical roles in gene regulation and RNA processing in cells. They are also useful for various applications in cell biology and synthetic biology. However, re-engineering novel and orthogonal RNA–RBP pairs from natural components remains c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789040/ https://www.ncbi.nlm.nih.gov/pubmed/34219162 http://dx.doi.org/10.1093/nar/gkab527 |