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The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus

The nucleotide messenger (p)ppGpp allows bacteria to adapt to fluctuating environments by reprogramming the transcriptome. Despite its well-recognized role in gene regulation, (p)ppGpp is only known to directly affect transcription in Proteobacteria by binding to the RNA polymerase. Here, we reveal...

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Detalles Bibliográficos
Autores principales: Anderson, Brent W, Schumacher, Maria A, Yang, Jin, Turdiev, Asan, Turdiev, Husan, Schroeder, Jeremy W, He, Qixiang, Lee, Vincent T, Brennan, Richard G, Wang, Jue D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789054/
https://www.ncbi.nlm.nih.gov/pubmed/34967415
http://dx.doi.org/10.1093/nar/gkab1281