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Structural and biochemical characterization of human Schlafen 5

The Schlafen family belongs to the interferon-stimulated genes and its members are involved in cell cycle regulation, T cell quiescence, inhibition of viral replication, DNA-repair and tRNA processing. Here, we present the cryo-EM structure of full-length human Schlafen 5 (SLFN5) and the high-resolu...

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Detalles Bibliográficos
Autores principales:	Metzner, Felix J, Huber, Elisabeth, Hopfner, Karl-Peter, Lammens, Katja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789055/ https://www.ncbi.nlm.nih.gov/pubmed/35037067 http://dx.doi.org/10.1093/nar/gkab1278

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