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Nonalternating purine pyrimidine sequences can form stable left-handed DNA duplex by strong topological constraint

In vivo, left-handed DNA duplex (usually refers to Z-DNA) is mainly formed in the region of DNA with alternating purine pyrimidine (APP) sequence and plays significant biological roles. It is well known that d(CG)(n) sequence can form Z-DNA most easily under negative supercoil conditions, but its es...

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Detalles Bibliográficos
Autores principales:	Li, Lin, Zhang, Yaping, Ma, Wanzhi, Chen, Hui, Liu, Mengqin, An, Ran, Cheng, Bingxiao, Liang, Xingguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789069/ https://www.ncbi.nlm.nih.gov/pubmed/34967416 http://dx.doi.org/10.1093/nar/gkab1283

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