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Condensin extrudes DNA loops in steps up to hundreds of base pairs that are generated by ATP binding events
The condensin SMC protein complex organizes chromosomal structure by extruding loops of DNA. Its ATP-dependent motor mechanism remains unclear but likely involves steps associated with large conformational changes within the ∼50 nm protein complex. Here, using high-resolution magnetic tweezers, we r...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789078/ https://www.ncbi.nlm.nih.gov/pubmed/34951453 http://dx.doi.org/10.1093/nar/gkab1268 |