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Ribosomal leaky scanning through a translated uORF requires eIF4G2

eIF4G2 (DAP5 or Nat1) is a homologue of the canonical translation initiation factor eIF4G1 in higher eukaryotes but its function remains poorly understood. Unlike eIF4G1, eIF4G2 does not interact with the cap-binding protein eIF4E and is believed to drive translation under stress when eIF4E activity...

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Detalles Bibliográficos
Autores principales: Smirnova, Victoria V, Shestakova, Ekaterina D, Nogina, Daria S, Mishchenko, Polina A, Prikazchikova, Tatiana A, Zatsepin, Timofei S, Kulakovskiy, Ivan V, Shatsky, Ivan N, Terenin, Ilya M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789081/
https://www.ncbi.nlm.nih.gov/pubmed/35018467
http://dx.doi.org/10.1093/nar/gkab1286

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