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The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II

Transcription factors (TFs) play a pivotal role in cell fate decision by coordinating gene expression programs. Although most TFs act at the DNA layer, few TFs bind RNA and modulate splicing. Yet, the mechanistic cues underlying TFs activity in splicing remain elusive. Focusing on the Drosophila Hox...

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Detalles Bibliográficos
Autores principales:	Carnesecchi, Julie, Boumpas, Panagiotis, van Nierop y Sanchez, Patrick, Domsch, Katrin, Pinto, Hugo Daniel, Borges Pinto, Pedro, Lohmann, Ingrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789087/ https://www.ncbi.nlm.nih.gov/pubmed/34931250 http://dx.doi.org/10.1093/nar/gkab1250

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