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Supplementing cultured human myotubes with hibernating bear serum results in increased protein content by modulating Akt/FOXO3a signaling

Hibernating bears remain in their dens for 5–7 months during winter and survive without eating or drinking while staying inactive. However, they maintain their physical functions with minimal skeletal muscle atrophy and metabolic dysfunction. In bears, resistance to skeletal muscle atrophy during hi...

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Detalles Bibliográficos
Autores principales: Miyazaki, Mitsunori, Shimozuru, Michito, Tsubota, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789107/
https://www.ncbi.nlm.nih.gov/pubmed/35077510
http://dx.doi.org/10.1371/journal.pone.0263085