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Supplementing cultured human myotubes with hibernating bear serum results in increased protein content by modulating Akt/FOXO3a signaling
Hibernating bears remain in their dens for 5–7 months during winter and survive without eating or drinking while staying inactive. However, they maintain their physical functions with minimal skeletal muscle atrophy and metabolic dysfunction. In bears, resistance to skeletal muscle atrophy during hi...
Autores principales: | Miyazaki, Mitsunori, Shimozuru, Michito, Tsubota, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789107/ https://www.ncbi.nlm.nih.gov/pubmed/35077510 http://dx.doi.org/10.1371/journal.pone.0263085 |
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