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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

BACKGROUND: Some individuals living with obesity may be relatively metabolically healthy, whilst others suffer from multiple conditions that may be linked to adverse metabolic effects or other factors. The extent to which the adverse metabolic component of obesity contributes to disease compared to...

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Detalles Bibliográficos
Autores principales: Martin, Susan, Tyrrell, Jessica, Thomas, E Louise, Bown, Matthew J, Wood, Andrew R, Beaumont, Robin N, Tsoi, Lam C, Stuart, Philip E, Elder, James T, Law, Philip, Houlston, Richard, Kabrhel, Christopher, Papadimitriou, Nikos, Gunter, Marc J, Bull, Caroline J, Bell, Joshua A, Vincent, Emma E, Sattar, Naveed, Dunlop, Malcolm G, Tomlinson, Ian PM, Lindström, Sara, Bell, Jimmy D, Frayling, Timothy M, Yaghootkar, Hanieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789289/
https://www.ncbi.nlm.nih.gov/pubmed/35074047
http://dx.doi.org/10.7554/eLife.72452