Cargando…
From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing
Many of the leading causes of death in humans, such as cardiovascular disease, type 2 diabetes and Alzheimer’s disease are influenced by biological mechanisms that become dysregulated with increasing age. Hence, by targeting these ageing-related mechanisms, we may be able to improve health in old ag...
Autores principales: | Baghdadi, Maarouf, Hinterding, Helena M, Partridge, Linda, Deelen, Joris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789301/ https://www.ncbi.nlm.nih.gov/pubmed/33690799 http://dx.doi.org/10.1093/bfgp/elab005 |
Ejemplares similares
-
Sex-specific effects of Cre expression in Syn1Cre mice
por: Baghdadi, Maarouf, et al.
Publicado: (2023) -
Reduced insulin signaling in neurons induces sex-specific health benefits
por: Baghdadi, Maarouf, et al.
Publicado: (2023) -
Targeting multimorbidity: Using healthspan and lifespan to identify biomarkers of ageing that pinpoint shared disease mechanisms
por: Deelen, Joris
Publicado: (2021) -
Ex Vivo Models to Decipher the Molecular Mechanisms of Genetic Notch Cardiovascular Disorders
por: Ristori, Tommaso, et al.
Publicado: (2021) -
Herbgenomics: Decipher molecular genetics of medicinal plants
por: Sun, Wei, et al.
Publicado: (2022)