The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation

Gene regulation via N6-methyladenosine (m(6)A) in mRNA involves RNA-binding proteins that recognize m(6)A via a YT521-B homology (YTH) domain. The plant YTH domain proteins ECT2 and ECT3 act genetically redundantly in stimulating cell proliferation during organogenesis, but several fundamental quest...

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Detalles Bibliográficos
Autores principales: Arribas-Hernández, Laura, Rennie, Sarah, Schon, Michael, Porcelli, Carlotta, Enugutti, Balaji, Andersson, Robin, Nodine, Michael D, Brodersen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789314/
https://www.ncbi.nlm.nih.gov/pubmed/34591013
http://dx.doi.org/10.7554/eLife.72377

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