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A Novel Method for Identifying Parkin Binding Agents in Complex Preparations of Herbal Medicines

Parkin is a crucial E3 ubiquitin ligase for initiating mitophagy through the PINK1/Parkin pathway. Regulating the expression and activity of parkin can remedy mitophagy and human disease. We developed an efficient method to isolate natural parkin ligands from herbal medicines by combining centrifuga...

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Detalles Bibliográficos
Autores principales:	Li, Feng-Jiao, Zhang, Fan, He, Xu-Dong, Liu, Xin, Mu, Jian-Kang, Yang, Min, Li, Yan-Qin, Gu, Wen, Yu, Jie, Yang, Xing-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789414/ https://www.ncbi.nlm.nih.gov/pubmed/35087614 http://dx.doi.org/10.1155/2022/3260243

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