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A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course
Biological separation and purification technology is the basic technology of modern biotechnology, which is widely used in the pharmaceutical industry, especially the biopharmaceutical industry. In recent years, the biopharmaceutical industry has had a lot of room for development in the development...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789454/ https://www.ncbi.nlm.nih.gov/pubmed/35087652 http://dx.doi.org/10.1155/2022/9728071 |
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author | He, Ying White, Marvin Gang, Wu Yan, Song |
author_facet | He, Ying White, Marvin Gang, Wu Yan, Song |
author_sort | He, Ying |
collection | PubMed |
description | Biological separation and purification technology is the basic technology of modern biotechnology, which is widely used in the pharmaceutical industry, especially the biopharmaceutical industry. In recent years, the biopharmaceutical industry has had a lot of room for development in the development of science and technology in South Korea, and the research on biopharmaceutical equipment and pharmaceutical technology has also achieved good research results. This article proposes a brief discussion on the design of biopharmaceutical separation and purification technology courses. In this study, by analyzing the synthesis potential of the secondary metabolites of the strain, using the α-glucosidase inhibition rate as an inspection indicator, the fermentation medium of the strain was optimized, and batch fermentation was carried out, and then, the metabolites were separated and purified, and the following conclusion was obtained: the α-glucosidase inhibition rate of the crude extract of the strain in the optimized fermentation medium is 35% higher than that of the initial medium. |
format | Online Article Text |
id | pubmed-8789454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-87894542022-01-26 A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course He, Ying White, Marvin Gang, Wu Yan, Song J Healthc Eng Research Article Biological separation and purification technology is the basic technology of modern biotechnology, which is widely used in the pharmaceutical industry, especially the biopharmaceutical industry. In recent years, the biopharmaceutical industry has had a lot of room for development in the development of science and technology in South Korea, and the research on biopharmaceutical equipment and pharmaceutical technology has also achieved good research results. This article proposes a brief discussion on the design of biopharmaceutical separation and purification technology courses. In this study, by analyzing the synthesis potential of the secondary metabolites of the strain, using the α-glucosidase inhibition rate as an inspection indicator, the fermentation medium of the strain was optimized, and batch fermentation was carried out, and then, the metabolites were separated and purified, and the following conclusion was obtained: the α-glucosidase inhibition rate of the crude extract of the strain in the optimized fermentation medium is 35% higher than that of the initial medium. Hindawi 2022-01-18 /pmc/articles/PMC8789454/ /pubmed/35087652 http://dx.doi.org/10.1155/2022/9728071 Text en Copyright © 2022 Ying He et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article He, Ying White, Marvin Gang, Wu Yan, Song A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title | A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title_full | A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title_fullStr | A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title_full_unstemmed | A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title_short | A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course |
title_sort | brief talk on the design of biopharmaceutical separation and purification technology course |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789454/ https://www.ncbi.nlm.nih.gov/pubmed/35087652 http://dx.doi.org/10.1155/2022/9728071 |
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