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MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

Mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) serving as delivery system have attracted extensive research interest, especially in cancer therapy. In our previous study, lipocalin-type prostaglandin D2 synthase (L-PGDS) showed inhibitory effects on gastric cancer growth. In this...

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Detalles Bibliográficos
Autores principales: You, Benshuai, Jin, Can, Zhang, Jiaxin, Xu, Min, Xu, Wenrong, Sun, Zixuan, Qian, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789473/
https://www.ncbi.nlm.nih.gov/pubmed/35087591
http://dx.doi.org/10.1155/2022/9668239