Natural compound library screening identifies Sanguinarine chloride for the treatment of SCLC by upregulating CDKN1A

OBJECTIVES: Small cell lung cancer (SCLC) is notorious for aggressive malignancy without effective treatment, and most patients eventually develop tumor progression with a poor prognosis. There is an urgent need for discovering novel antitumor agents or therapeutic strategies for SCLC. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Zhong, Mingtian, Li, Xun, Zhao, Fengyun, Huang, Yanni, Long, Yihao, Chen, Kaizhao, Tian, Xuemei, Liu, Ming, Ma, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789530/
https://www.ncbi.nlm.nih.gov/pubmed/35066462
http://dx.doi.org/10.1016/j.tranon.2022.101345

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