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Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality

BACKGROUND: Emergency warning systems (EWS) are becoming a standard of care, but have unproven screening value in early critical illness. Similarly, emergency response team (ERT) care is of uncertain value. These questions are most controversial in mixed patient populations, where screening performa...

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Autores principales: Nestor, Claire C., Donnelly, Maria, Connors, Siobhán, Morrison, Patricia, Boylan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789627/
https://www.ncbi.nlm.nih.gov/pubmed/33689132
http://dx.doi.org/10.1007/s11845-021-02558-7
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author Nestor, Claire C.
Donnelly, Maria
Connors, Siobhán
Morrison, Patricia
Boylan, John
author_facet Nestor, Claire C.
Donnelly, Maria
Connors, Siobhán
Morrison, Patricia
Boylan, John
author_sort Nestor, Claire C.
collection PubMed
description BACKGROUND: Emergency warning systems (EWS) are becoming a standard of care, but have unproven screening value in early critical illness. Similarly, emergency response team (ERT) care is of uncertain value. These questions are most controversial in mixed patient populations, where screening performance might vary, and intensivist-led ERT care might divert resources from existing patients. AIMS: To examine triggering events, disposition and outcome data for an intensivist-staffed EWS-ERT system. METHODS: We analysed process and outcome data over three years, classing EWS-triggered patients into three categories (non-escalated, escalated ward care and critical care transfer). The relationships between EWS data, pre-triggering clinical data, and patient disposition and outcome were examined. RESULTS: There were 1675 calls in 1190 patients. Most occurred later during admission, with critical care transfer in a minority; the rest were followed by escalated or non-escalated ward care. Patients transferred to critical care had high mortality (40.3%); less than half of patient transfers occurred following triggering EWS score predicted overall hospital mortality, but not mortality after critical care. CONCLUSIONS: In a diverse hospital population, most triggering patients did not receive critical care and most critical care transfers occurred without triggering. Triggering was an insensitive screening measure for critical illness, followed by poor outcome. Higher scores predicted higher probability of transfer, but not later mortality, suggesting that EWS is being used as a decision aid but is not a true severity of illness score. Other, non-EWS data are needed for earlier detection and for prioritizing access to critical care.
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spelling pubmed-87896272022-02-02 Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality Nestor, Claire C. Donnelly, Maria Connors, Siobhán Morrison, Patricia Boylan, John Ir J Med Sci Original Article BACKGROUND: Emergency warning systems (EWS) are becoming a standard of care, but have unproven screening value in early critical illness. Similarly, emergency response team (ERT) care is of uncertain value. These questions are most controversial in mixed patient populations, where screening performance might vary, and intensivist-led ERT care might divert resources from existing patients. AIMS: To examine triggering events, disposition and outcome data for an intensivist-staffed EWS-ERT system. METHODS: We analysed process and outcome data over three years, classing EWS-triggered patients into three categories (non-escalated, escalated ward care and critical care transfer). The relationships between EWS data, pre-triggering clinical data, and patient disposition and outcome were examined. RESULTS: There were 1675 calls in 1190 patients. Most occurred later during admission, with critical care transfer in a minority; the rest were followed by escalated or non-escalated ward care. Patients transferred to critical care had high mortality (40.3%); less than half of patient transfers occurred following triggering EWS score predicted overall hospital mortality, but not mortality after critical care. CONCLUSIONS: In a diverse hospital population, most triggering patients did not receive critical care and most critical care transfers occurred without triggering. Triggering was an insensitive screening measure for critical illness, followed by poor outcome. Higher scores predicted higher probability of transfer, but not later mortality, suggesting that EWS is being used as a decision aid but is not a true severity of illness score. Other, non-EWS data are needed for earlier detection and for prioritizing access to critical care. Springer International Publishing 2021-03-10 2022 /pmc/articles/PMC8789627/ /pubmed/33689132 http://dx.doi.org/10.1007/s11845-021-02558-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Nestor, Claire C.
Donnelly, Maria
Connors, Siobhán
Morrison, Patricia
Boylan, John
Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title_full Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title_fullStr Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title_full_unstemmed Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title_short Early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
title_sort early warning scores and critical care transfer – patient heterogeneity, low sensitivity, high mortality
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789627/
https://www.ncbi.nlm.nih.gov/pubmed/33689132
http://dx.doi.org/10.1007/s11845-021-02558-7
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