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Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice

Heart failure (HF) is the only cardiovascular disease with an ever increasing incidence. HF, through reduced functional capacity, frequent exacerbations of disease, and repeated hospitalizations, results in poorer quality of life, decreased work productivity, and significantly increased costs of the...

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Autores principales: Chuda, Anna, Banach, Maciej, Maciejewski, Marek, Bielecka-Dabrowa, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789698/
https://www.ncbi.nlm.nih.gov/pubmed/33595788
http://dx.doi.org/10.1007/s11845-020-02477-z
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author Chuda, Anna
Banach, Maciej
Maciejewski, Marek
Bielecka-Dabrowa, Agata
author_facet Chuda, Anna
Banach, Maciej
Maciejewski, Marek
Bielecka-Dabrowa, Agata
author_sort Chuda, Anna
collection PubMed
description Heart failure (HF) is the only cardiovascular disease with an ever increasing incidence. HF, through reduced functional capacity, frequent exacerbations of disease, and repeated hospitalizations, results in poorer quality of life, decreased work productivity, and significantly increased costs of the public health system. The main challenge in the treatment of HF is the availability of reliable prognostic models that would allow patients and doctors to develop realistic expectations about the prognosis and to choose the appropriate therapy and monitoring method. At this moment, there is a lack of universal parameters or scales on the basis of which we could easily capture the moment of deterioration of HF patients’ condition. Hence, it is crucial to identify such factors which at the same time will be widely available, cheap, and easy to use. We can find many studies showing different predictors of unfavorable outcome in HF patients: thorough assessment with echocardiography imaging, exercise testing (e.g., 6-min walk test, cardiopulmonary exercise testing), and biomarkers (e.g., N-terminal pro-brain type natriuretic peptide, high-sensitivity troponin T, galectin-3, high-sensitivity C-reactive protein). Some of them are very promising, but more research is needed to create a specific panel on the basis of which we will be able to assess HF patients. At this moment despite identification of many markers of adverse outcomes, clinical decision-making in HF is still predominantly based on a few basic parameters, such as the presence of HF symptoms (NYHA class), left ventricular ejection fraction, and QRS complex duration and morphology.
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spelling pubmed-87896982022-02-02 Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice Chuda, Anna Banach, Maciej Maciejewski, Marek Bielecka-Dabrowa, Agata Ir J Med Sci Review Article Heart failure (HF) is the only cardiovascular disease with an ever increasing incidence. HF, through reduced functional capacity, frequent exacerbations of disease, and repeated hospitalizations, results in poorer quality of life, decreased work productivity, and significantly increased costs of the public health system. The main challenge in the treatment of HF is the availability of reliable prognostic models that would allow patients and doctors to develop realistic expectations about the prognosis and to choose the appropriate therapy and monitoring method. At this moment, there is a lack of universal parameters or scales on the basis of which we could easily capture the moment of deterioration of HF patients’ condition. Hence, it is crucial to identify such factors which at the same time will be widely available, cheap, and easy to use. We can find many studies showing different predictors of unfavorable outcome in HF patients: thorough assessment with echocardiography imaging, exercise testing (e.g., 6-min walk test, cardiopulmonary exercise testing), and biomarkers (e.g., N-terminal pro-brain type natriuretic peptide, high-sensitivity troponin T, galectin-3, high-sensitivity C-reactive protein). Some of them are very promising, but more research is needed to create a specific panel on the basis of which we will be able to assess HF patients. At this moment despite identification of many markers of adverse outcomes, clinical decision-making in HF is still predominantly based on a few basic parameters, such as the presence of HF symptoms (NYHA class), left ventricular ejection fraction, and QRS complex duration and morphology. Springer International Publishing 2021-02-17 2022 /pmc/articles/PMC8789698/ /pubmed/33595788 http://dx.doi.org/10.1007/s11845-020-02477-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Chuda, Anna
Banach, Maciej
Maciejewski, Marek
Bielecka-Dabrowa, Agata
Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title_full Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title_fullStr Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title_full_unstemmed Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title_short Role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
title_sort role of confirmed and potential predictors of an unfavorable outcome in heart failure in everyday clinical practice
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789698/
https://www.ncbi.nlm.nih.gov/pubmed/33595788
http://dx.doi.org/10.1007/s11845-020-02477-z
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