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FOXO1 forkhead domain mutants in B-cell lymphoma lack transcriptional activity

Somatic point mutations of the FOXO1 transcription factor were reported in non-Hodgkin lymphoma including diffuse large B-cell lymphoma, follicular lymphoma and Burkitt lymphoma. These alterations were associated with a poor prognosis and resistance to therapy. Nearly all amino acid substitutions ar...

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Detalles Bibliográficos
Autores principales:	Sablon, Ariane, Bollaert, Emeline, Pirson, Constance, Velghe, Amélie I., Demoulin, Jean-Baptiste
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789783/ https://www.ncbi.nlm.nih.gov/pubmed/35079069 http://dx.doi.org/10.1038/s41598-022-05334-4

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