T cell subtype profiling measures exhaustion and predicts anti-PD-1 response

Anti-PD-1 therapy can provide long, durable benefit to a fraction of patients. The on-label PD-L1 test, however, does not accurately predict response. To build a better biomarker, we created a method called T Cell Subtype Profiling (TCSP) that characterizes the abundance of T cell subtypes (TCSs) in...

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Detalles Bibliográficos
Autores principales: Schillebeeckx, Ian, Earls, Jon, Flanagan, Kevin C., Hiken, Jeffrey, Bode, Alex, Armstrong, Jon R., Messina, David N., Adkins, Douglas, Ley, Jessica, Alborelli, Ilaria, Jermann, Philip, Glasscock, Jarret I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789795/
https://www.ncbi.nlm.nih.gov/pubmed/35079117
http://dx.doi.org/10.1038/s41598-022-05474-7

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