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Asthma in paediatric intensive care in England residents: observational study

Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU...

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Autores principales: Mukherjee, Mome, Cunningham, Steve, Bhuia, Mohammad Romel, Lo, Tsz-Yan Milly, Been, Jasper V., Sheikh, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789863/
https://www.ncbi.nlm.nih.gov/pubmed/35079067
http://dx.doi.org/10.1038/s41598-022-05414-5
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author Mukherjee, Mome
Cunningham, Steve
Bhuia, Mohammad Romel
Lo, Tsz-Yan Milly
Been, Jasper V.
Sheikh, Aziz
author_facet Mukherjee, Mome
Cunningham, Steve
Bhuia, Mohammad Romel
Lo, Tsz-Yan Milly
Been, Jasper V.
Sheikh, Aziz
author_sort Mukherjee, Mome
collection PubMed
description Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU database, was queried for asthma as the primary reason for admission, of children resident in England from April 2006 until March 2013. There were 2195 admissions to PICU for a median stay of 1.4 days. 59% were males and 51% aged 0–4 years. The fourth and fifth most deprived quintiles represented 61% (1329) admissions and 73% (11) of the 15 deaths. Deaths were most frequent in 10–14 years age (n = 11, 73%), with no deaths in less than 5 years age. 38% of admissions (828/2193) received invasive ventilation, which was more frequent with increasing deprivation (13% (108/828) in least deprived to 31% (260/828) in most deprived) and with decreasing age (0–4-year-olds: 49%, 409/828). This first multi-centre PICU study in England found that children from more deprived neighbourhoods represented the majority of asthma admissions, invasive ventilation and deaths in PICU. Children experiencing socioeconomic deprivation could benefit from enhanced asthma support in the community.
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spelling pubmed-87898632022-01-27 Asthma in paediatric intensive care in England residents: observational study Mukherjee, Mome Cunningham, Steve Bhuia, Mohammad Romel Lo, Tsz-Yan Milly Been, Jasper V. Sheikh, Aziz Sci Rep Article Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU database, was queried for asthma as the primary reason for admission, of children resident in England from April 2006 until March 2013. There were 2195 admissions to PICU for a median stay of 1.4 days. 59% were males and 51% aged 0–4 years. The fourth and fifth most deprived quintiles represented 61% (1329) admissions and 73% (11) of the 15 deaths. Deaths were most frequent in 10–14 years age (n = 11, 73%), with no deaths in less than 5 years age. 38% of admissions (828/2193) received invasive ventilation, which was more frequent with increasing deprivation (13% (108/828) in least deprived to 31% (260/828) in most deprived) and with decreasing age (0–4-year-olds: 49%, 409/828). This first multi-centre PICU study in England found that children from more deprived neighbourhoods represented the majority of asthma admissions, invasive ventilation and deaths in PICU. Children experiencing socioeconomic deprivation could benefit from enhanced asthma support in the community. Nature Publishing Group UK 2022-01-25 /pmc/articles/PMC8789863/ /pubmed/35079067 http://dx.doi.org/10.1038/s41598-022-05414-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mukherjee, Mome
Cunningham, Steve
Bhuia, Mohammad Romel
Lo, Tsz-Yan Milly
Been, Jasper V.
Sheikh, Aziz
Asthma in paediatric intensive care in England residents: observational study
title Asthma in paediatric intensive care in England residents: observational study
title_full Asthma in paediatric intensive care in England residents: observational study
title_fullStr Asthma in paediatric intensive care in England residents: observational study
title_full_unstemmed Asthma in paediatric intensive care in England residents: observational study
title_short Asthma in paediatric intensive care in England residents: observational study
title_sort asthma in paediatric intensive care in england residents: observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789863/
https://www.ncbi.nlm.nih.gov/pubmed/35079067
http://dx.doi.org/10.1038/s41598-022-05414-5
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