Cargando…
Asthma in paediatric intensive care in England residents: observational study
Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789863/ https://www.ncbi.nlm.nih.gov/pubmed/35079067 http://dx.doi.org/10.1038/s41598-022-05414-5 |
_version_ | 1784639870232166400 |
---|---|
author | Mukherjee, Mome Cunningham, Steve Bhuia, Mohammad Romel Lo, Tsz-Yan Milly Been, Jasper V. Sheikh, Aziz |
author_facet | Mukherjee, Mome Cunningham, Steve Bhuia, Mohammad Romel Lo, Tsz-Yan Milly Been, Jasper V. Sheikh, Aziz |
author_sort | Mukherjee, Mome |
collection | PubMed |
description | Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU database, was queried for asthma as the primary reason for admission, of children resident in England from April 2006 until March 2013. There were 2195 admissions to PICU for a median stay of 1.4 days. 59% were males and 51% aged 0–4 years. The fourth and fifth most deprived quintiles represented 61% (1329) admissions and 73% (11) of the 15 deaths. Deaths were most frequent in 10–14 years age (n = 11, 73%), with no deaths in less than 5 years age. 38% of admissions (828/2193) received invasive ventilation, which was more frequent with increasing deprivation (13% (108/828) in least deprived to 31% (260/828) in most deprived) and with decreasing age (0–4-year-olds: 49%, 409/828). This first multi-centre PICU study in England found that children from more deprived neighbourhoods represented the majority of asthma admissions, invasive ventilation and deaths in PICU. Children experiencing socioeconomic deprivation could benefit from enhanced asthma support in the community. |
format | Online Article Text |
id | pubmed-8789863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-87898632022-01-27 Asthma in paediatric intensive care in England residents: observational study Mukherjee, Mome Cunningham, Steve Bhuia, Mohammad Romel Lo, Tsz-Yan Milly Been, Jasper V. Sheikh, Aziz Sci Rep Article Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU database, was queried for asthma as the primary reason for admission, of children resident in England from April 2006 until March 2013. There were 2195 admissions to PICU for a median stay of 1.4 days. 59% were males and 51% aged 0–4 years. The fourth and fifth most deprived quintiles represented 61% (1329) admissions and 73% (11) of the 15 deaths. Deaths were most frequent in 10–14 years age (n = 11, 73%), with no deaths in less than 5 years age. 38% of admissions (828/2193) received invasive ventilation, which was more frequent with increasing deprivation (13% (108/828) in least deprived to 31% (260/828) in most deprived) and with decreasing age (0–4-year-olds: 49%, 409/828). This first multi-centre PICU study in England found that children from more deprived neighbourhoods represented the majority of asthma admissions, invasive ventilation and deaths in PICU. Children experiencing socioeconomic deprivation could benefit from enhanced asthma support in the community. Nature Publishing Group UK 2022-01-25 /pmc/articles/PMC8789863/ /pubmed/35079067 http://dx.doi.org/10.1038/s41598-022-05414-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Mukherjee, Mome Cunningham, Steve Bhuia, Mohammad Romel Lo, Tsz-Yan Milly Been, Jasper V. Sheikh, Aziz Asthma in paediatric intensive care in England residents: observational study |
title | Asthma in paediatric intensive care in England residents: observational study |
title_full | Asthma in paediatric intensive care in England residents: observational study |
title_fullStr | Asthma in paediatric intensive care in England residents: observational study |
title_full_unstemmed | Asthma in paediatric intensive care in England residents: observational study |
title_short | Asthma in paediatric intensive care in England residents: observational study |
title_sort | asthma in paediatric intensive care in england residents: observational study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789863/ https://www.ncbi.nlm.nih.gov/pubmed/35079067 http://dx.doi.org/10.1038/s41598-022-05414-5 |
work_keys_str_mv | AT mukherjeemome asthmainpaediatricintensivecareinenglandresidentsobservationalstudy AT cunninghamsteve asthmainpaediatricintensivecareinenglandresidentsobservationalstudy AT bhuiamohammadromel asthmainpaediatricintensivecareinenglandresidentsobservationalstudy AT lotszyanmilly asthmainpaediatricintensivecareinenglandresidentsobservationalstudy AT beenjasperv asthmainpaediatricintensivecareinenglandresidentsobservationalstudy AT sheikhaziz asthmainpaediatricintensivecareinenglandresidentsobservationalstudy |